Kyoto University researchers claim discovery of body clocks reset button

Vasopressin Body Kyoto Mice

Jet lag is a common problem among people travelling from one time zone to another. Workers on shifting schedules are also having a hard time making adjustments. Both situations impose disruptions in daily routine. But researchers from the Kyoto University claimed to have found the body’s ‘reset button.’

The research team was able to see results from groups of mice – one with and the other without vasopressin receptors – through a modified environment. By suppressing vasopressin, a hormone produced in the body, the mice without vasopressin receptors were able to adjust when put back in eight hours in a day. As for the normal mice, adjustment took six days. They also got the same result using a vasopressin drug. The team’s discovery was published in Science Magazine, the academic journal of the American Association for the Advancement of Science (AAAS) on Friday.

Vasopressin is mainly responsible for water retention in the body. Turned out, based on the research team from Kyoto University, the hormone also plays a significant role in keeping the body’s circadian rhythm or body clock. “Studies have shown that chronic jet lag and rotating shift work can increase an individual’s risk of developing hypertension, obesity, and other metabolic disorders,” the researchers concluded ( via ).