October 13, 2012 - A magnetic method of killing cancer cells
has been developed by scientists in South Korea.The technique uses a magnetic field to flip a "self-destruct" switch in tumours.
Researchers have demonstrated that the process works in bowel cancer
cells and living laboratory fish. Programmed cell death, or apoptosis, is one of the body's ways of getting rid of old, faulty or infected cells.
In response to certain signals, the doomed cell shrinks and breaks into fragments. These are then engulfed and consumed by amoeba-like immune cells.
Often in cancer, apoptosis fails and cells are allowed to keep dividing uncontrollably.
The magnetic therapy involves creating tiny iron nanoparticles attached to antibodies which bind to "receptor" molecules on tumour cells. When the magnetic field is applied, the molecules cluster together, automatically triggering the "death signal" that sets off apoptosis.
In laboratory experiments, bowel cancer
cells were exposed to the nanoparticles and placed between two magnets. The cells were designed to light up green to signal that apoptopic clustering was taking place.