Gain of function research

Gain of function research

Gain of function research is a term used to describe any field of medical research which alters an organism or disease in a way that increases pathogenesis, transmissibility, or host range. This research is intended to reveal targets to better predict emerging infectious diseases and to develop vaccines and therapeutics. For example, influenza B can only infect humans and harbor seals. Introducing a mutation that would allow influenza B to infect rabbits in a controlled laboratory situation would be considered a “gain of function” experiment as the virus did not previously have that function. However, such an experiment could help reveal which parts of the virus are responsible for its host range, enabling the creation of antiviral medicines which block this function. In virology, gain-of-function research is employed with the intention of better understanding current and future pandemics.

imo

gain of function research is clearly unethical and the ban on them should be rigorously enforced. this is now the new nuclear disarmament.

2 Likes